Today, I faced an error in customer place when I restart the Application Virtualization Management Server service, saying that: "Windows could not start the Application Virtualization Management Server on Local Computer. For more information, review the System Event Log. If this is a non-Microsoft service, contact the service vendor, and refer to service-specific error code 268480327."
Solution: Reboot your App V server. After reboot, the server will be functioning again. =)